This great herb needs no introduction when it comes to its immense health benefits. Yes, I am talking about the King of Herbs – ‘Ashwagandha’ and in this article, we will evaluate some studies done on this magnificent herbs.

Here are some reviews and extracts from the studies done on Ashwagandha for a better understanding of its medicinal and curative powers and its beneficial effects on our health.

Ashwagandha Research Papers Extracts –  A Potent Herb

  1. The treatment group that was given the high-concentration full-spectrum Ashwagandha root extract exhibited a significant reduction (P<0.0001) in scores on all the stress-assessment scales on Day 60, relative to the placebo group. The serum cortisol levels were substantially reduced (P=0.0006) in the Ashwagandha group, relative to the placebo group.
  2. The available scientific data support the conclusion that Ashwagandha is a real potent regenerative tonic (Rasayana of Ayurveda), due to its multiple pharmacological actions like anti-stress, neuroprotective, antitumor, anti-arthritic, analgesic and anti-inflammatory, etc. It is useful for different types of diseases like Parkinson, dementia, memory loss, stress-induced diseases, malignoma and others.
  3. Ashwagandha was tested for its anti-aging properties in a double-blind clinical trial. A group of 101 healthy males, 50-59 years old was given the herb at a dosage of 3 grams daily for one year. The subjects experienced significant improvement in hemoglobin, red blood cell count, hair melanin, and seated stature. Serum cholesterol decreased, and nail calcium was preserved. Seventy percent of the research subjects reported improvement in sexual performance.
  4. This study reports that ashwagandha supplementation is associated with significant weight loss and increases in muscle mass and strength and suggests that ashwagandha supplementation may be useful in conjunction with a resistance training program.
  5. Improvements in power output have been noted in trained persons subject to a sprint test and in sedentary persons who simply took the supplement as well as untrained people who began strength training.
  6. There is a decrease in total cholesterol of around 10% when ashwagandha (water extract of the roots) is ingested. It is notable, however, since this appears to occur in all persons regardless of whether they have high cholesterol or not.
  7. It is concluded that Ashwagandha, in addition to having a tumor inhibitory effect, also acts as a radiosensitizer and heat enhances these effects. The severe depletion in the tumor GSH content by the combination treatment must have enhanced the tumor response, as the inherent protection by the thiol will be highly reduced.
  8. Withaferin A gave a sensitizer enhancement ratio of 1.5 for in vitro cell killing of V79 Chinese hamster cells at a nontoxic concentration of approximately two microM. The mechanism of action of this compound is not known. The studies so far indicate that W. somnifera could prove to be a good natural source of a potent and relatively safe radiosensitizer/chemotherapeutic agent.
  9. Ashwagandha is an effective herbal remedy for stress and infertility. It improves blood circulation throughout the body and enhances sperm quality naturally. Apart from curing sperm problems, intake of Ashwagandha helps in improving the overall health and well-being of a person. It relaxes the nerve cells and reduces the occurrence of various health disorders.
  10. In the present study, we evaluated the antibacterial activity of ashwagandha [Withania somnifera L. Dunal (Solanaceae; root and leaves)], an Indian traditional medicinal plant against pathogenic bacteria. Both aqueous, as well as alcoholic extracts of the plant (root as well as leaves), were found to possess strong antibacterial activity against a range of bacteria, as revealed by in vitro Agar Well Diffusion Method.
  11. Ashwagandha and demonstrated withanone as a cancer inhibitory factor (i-Factor). In the present study, we fractionated the i-Extract to its components by silica gel column chromatography and subjected them to cell-based activity analyses. We found that the cancer inhibitory leaf extract (i-Extract) has, at least, seven components that could cause cancer cell killing.
  12. Several experimental studies are conducted on Ashwagandha and its constituents providing the scientific bases for the activities reported in Ayurveda. A significant amount of investigations have been carried out on anticancer and chemoprotective activities of Ashwagandha indicate the drug is a potentially useful adjunct for patients undergoing radiation and chemotherapy.

Conclusion

Ashwagandha has proven itself to be a potent herb with amazing curative powers that heal and prevent numerous diseases and possesses strong anti-stress, neuroprotective, antitumor, anti-arthritic, analgesic and anti-inflammatory properties.